22 Health Benefits of CBD/Cannabidiol

Most people try to minimize the number of pharmaceuticals they consume. In some cases, it’s completely unavoidable, but in others, there are choices.

Pharmaceuticals, in many cases are addictive, and they often come with a laundry list of side effects. Some of the side effects are dangerous, others can even be deadly.

Recent research shows that CBD Hemp Oil, has a variety of holistic wellness and health benefits, highlighting the many ways in which the use of cannabinoids can improve general health. As more and more people consider the volume of medications they are taking, CBD products like CHOI provide an all-natural alternative.

  

1. CBD Fights Against Cancer

CBD and other chemicals found in Cannabis have an antitumor effect and could be used to improve standard treatments (R).

CBD successfully stopped cancer cells in multiple different cervical cancer cells (RR2).

CBD increased tumor cell death in leukemia and colon cancer (RR2R3).

It also decreased human glioma cell growth and invasion, thus suggesting a possible role of CBD as an antitumor agent (RR2).

Cannabinoids may be promising tools in combination therapy for breast and prostate cancer, due to their direct antitumor effects, their ability to improve the effectiveness of conventional antitumor drugs, and their usefulness as a treatment to reduce pain (RR2R3).

Anticancer Mechanisms:

  • CBD decreased the ability of the cancer cells to produce energy, leading to their death (R).
  • CBD treatment helps lymphokine-activated killer (LAK) cells kill cancer cells better (R).
  • CBD blocks CPR55 signaling, decreasing cancer cell proliferation.

 

2. CBD Reduces Inflammation and Autoimmunity

Due to its anti-inflammatory role, CBD is a very promising therapeutic agent for a variety of inflammatory and pain-associated disorders.

CBD Can Blunt Th1 and Th2 Dominance

In a rat model of asthma, both Th1 (IL-6 and TNF-a) and Th2 (IL-4, IL-5, IL-13) responses are reduced by CBD treatment (R).

CBD decreased the production and release of inflammatory cytokines such as Th1 (TNF-alpha, IFN-gamma, and IL-6), Th2 (IL-4), and IL-8 (RR2).

CBD Helps with Th17 Dominance

CBD can help suppressing Th17 dominance, which means that it can help with some Th17-dominant autoimmune diseases (R).

Other Anti-inflammatory Mechanisms:

  • CBD reduces the growth and mobilization of neutrophils(R).
  • CBD reduces the inflammatory Macrophage Inflammatory Protein-1 (MIP-1 alpha, MIP-1beta) (R).

 

3. CBD May Protect from Neurodegenerative Diseases

CBD was found to prevent toxic effects of neurotransmitter glutamate and radical oxygen species (ROS) in the brain, thus preventing brain cell death (RR2).

CBD has antioxidant activity greater than vitamin C (ascorbic acid) or vitamin E (α-tocopherol) (R).

CBD may also protect brain cells from beta-amyloid toxicity, making it a potential therapy in Alzheimer’s and Parkinson’s disease (RR2).

CBD may also protect the brain from in cases where blood flow is reduced (ischemia) (RR2).

Early human studies showed a dose-related improvement in patients with Parkinson’s disease treated with 100–600 mg/day of CBD over a 6-week period (R).

However, another study failed to show any beneficial effect of a mixture of other phytocannabinoids and CBD either on Parkinson’s disease or dyskinesia (R).

CBD has been shown to reverse cognitive deficits of Alzheimer’s disease in animal models (R).

CBD, due to its anti-inflammatory and antioxidant properties, may be a promising agent to treat and prolong survival in Amyotrophic Lateral Sclerosis (ALS) patients (R).

 

4. CBD May Relieve Multiple Sclerosis Symptoms

Cannabis derivatives may relieve symptoms in multiple sclerosis patients (R).

A combination of CBD and other phytocannabinoids is effective and well tolerated in the treatment of muscle tightness, pain, sleep disturbances, and loss of bladder control (urinary incontinence) in people with multiple sclerosis (RR2R3).

 

5. CBD Has Therapeutic Potential for Schizophrenia

CBD is a potential treatment for psychosis (RR2).

CBD improves the symptoms of schizophrenia, but the mechanism of action is unknown (RR2).

Studies suggest that CBD has similar effects as atypical anti-psychotic drugs, but with fewer side effects (R).

 

6. CBD Helps with Epileptic Seizures

CBD may be a promising therapy for treatment-resistant epilepsy (RR2).

In a survey including parents of children with treatment-resistant epilepsy, 84% of parents reported a reduction in their child’s seizure frequency while taking CBD (R).

These children also experienced increased alertness, better mood and improved sleepdrowsiness and fatigue occurred as side effects (R).

After 3 months of treatment with a purified 98% oil-based CBD extract, 39% of children with treatment-resistant epilepsy had a more than a 50% reduction in seizures (R).

7 out of 8 patients suffering from secondary generalized epilepsy and resistant to antiepileptic drugs had improvement of their disease state after receiving 200-300 mg/d of cannabidiol for up to 4.5 months (R).

 

7. CBD Reduces Anxiety

Cannabidiol reduces anxiety in both healthy individuals and patients with social anxiety disorder (RR2).

Studies showed that CBD significantly reduced anxiety and discomfort caused by public speaking (RR2).

CBD also reduced anxiety caused by the use of THC (R).

Researchers suggest that it may be effective for panic disorder, obsessive compulsive disorder and post-traumatic stress disorder (R).

CBD is a potential therapy for posttraumatic stress disorder (PTSD) treatment (R).

 

8. CBD Relieves Pain

Studies suggest that cannabinoids may be a new class of drugs for the treatment of chronic pain (RR2).

CBD significantly decreased chronic inflammatory and neuropathic pain in rodents (R).

Cannabidiol, especially in a combination with other phytocannabinoids, shows promising results for the treatment of postoperative pain, chronic pain associated with multiple sclerosis, cancer, rheumatoid arthritis and neuropathic pain (RR2R3).

CBD, a combination of CBD and other phytocannabinoids as a sublingual spray, is effective in treating neuropathic pain in patients with multiple sclerosis and in cancer patients with advanced pain (RR2).

Study had showed that CBD and opioids act together to relieve pain (R).

 

9. CBD May Be Beneficial in Rheumatoid Arthritis

Due to its anti-inflammatory effect, cannabinoids may provide relief of joint pain and swelling, and decrease joint destruction and disease progression (R).

Administration of CBD protected joints against severe damage, decreased progression and produced improvement of arthritis in animal models (R).

The first controlled trial showed that administration of CBD over five weeks produced significant improvements in intensity of pain on movement and at rest, quality of sleep, and inflammation. No serious adverse effects were observed (R).

 

10. Cannabidiol Relieves Nausea and Increases Appetite

Study showed that CBD relieved nausea and vomiting when it was given to rats (R).

Researchers found that CBD in low doses decreases nausea and vomiting produced by toxic drugs, but in high doses it increases nausea or has no effect in animal models (RR2).

According to the National Cancer Institute, CBD increases appetite by binding to cannabinoid receptors in the body (R).

 

11. Cannabidiol Lowers Incidence of Diabetes

The study which included 4,657 adult men and women showed that current marijuana use was associated with 16% lower fasting insulin levels, and smaller waist circumferences, a factor connected to the onset of diabetes (R).

Cannabidiol significantly reduces the development of diabetes in young non-obese mice, from 86% in non-treated mice to only 30% in mice treated with CBD (RR2).

Cannabidiol can inhibit and delay the destruction of insulin-producing pancreatic cells and the production of inflammatory cytokines in diabetics (R).

This data strengthen assumptions that CBD, which is known to be safe in man, can possibly be used as a therapeutic agent for treatment of type 1 diabetes at an early stage of the disease (R).

 

12. Cannabidiol May Promote Heart Health

Study reported that CBD caused dilation of arteries, and protected blood vessel from damage in animal models (R).

CBD reduced the infarct size (size of damage from clogged blood vessels) in the heart and brain, and irregular heart rhythms in animal models (RR2).

Studies showed that CBD reduced the heart rate and blood pressure in response to anxiety or stressful situations (RR2).

CBD also influenced white blood cell function and platelet aggregation (RR2).

However, further work is required to prove the ability of CBD to prevent the development of heart and blood vessels disorders in humans.

 

13. Cannabidiol May Treat Depression

According to researchers, CBD has antidepressant-like effects in mice (R, R2).

Study found that antidepressant effects of CBD were fast, continuous over time, and comparable to a common tricyclic medication imipramine, also known as Tofranil (RR2).

 

14. Cannabidiol May Help with Inflammatory Bowel Disease

Studies confirmed that CBD prevents colitis in animal models of IBD (RR2R3).

The combination of CBD and other phytocannabinoids may reduce inflammation and relieve symptoms of IBD such as abdominal pain, diarrhea and reduced appetite (R).

Studies also showed that CBD may be a good candidate to normalize gut motility in patients with inflammatory bowel disease (RR2).

CBD may reduce gut inflammation severity through activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) (RR2).

 

15. Cannabidiol May Protect Against Bacteria

CBD showed some antimicrobial activity against methicillin-resistant Staphylococcus Aureus (MRSA), a bacterium that can cause difficult-to-treat infection (R).

 

16. Cannabidiol May Protect from Mad Cow Disease

Cannabidiol has been shown to inhibit prions, the proteins that cause fatal neurodegenerative diseases like Creutzfeldt-Jakob disease and mad cow disease, increasing the survival time of infected mice by almost a week (R).

 

17. Cannabidiol Promotes Bone Growth

Rodents with broken limbs healed much faster when treated with CBD (R).

 

18. Cannabidiol May Help with Insomnia

Research suggests that taking CBD before bed improves sleep in people with insomnia (R).

 

19. Cannabidiol May be Effective for Treating Substance Use Disorders

Studies suggest that CBD may be therapy for substance use disorders.

CBD reduced the rewarding effects of morphine and reduced drug seeking of heroin in animal model (RR2).

 

20. Cannabidiol May Help with Quitting Smoking

Research suggests that inhaling cannabidiol for a week might reduce the number of cigarettes smoked by about 40%, without increasing craving for nicotine (R).

 

21. Cannabidiol May Provide Treatment for Acne

CBD decreases lipid synthesis and proliferation of human sebaceous glands, and has anti-inflammatory effect on sebaceous glands, thus having a potential as a therapeutic agent for the treatment of acne vulgaris (R).

 

22. Cannabidiol May Play a Role in Psoriasis

CBD reduces the growth of skin cells (keratinocytes), playing a potential role in the treatment of psoriasis (R).